We worked with Microsoft extensively throughout the Server 2012 TAP program providing feedback in various areas. We encountered an issue late in the program when creating a Server 2012 cluster on our production domain. We did not see this same issue in any lab environment, or in our development environment which mirrors production.
When attempting to create the cluster, the wizard would fail when creating the AD objects. We confirmed that the user had proper permissions, and did not encounter the same issues creating 2008 or 2008 R2 clusters on our production domain. After working with Microsoft, they recommended we install KB 976424 on our production domain controllers. After installing this hotfix and rebooting all of the domain controllers, we were able to create a Server 2012 cluster on our 2008 domain without issue.